Striatal microRNA controls cocaine intake through CREB signaling

Cocaine addiction is characterized by a gradual loss of control over drug use, but molecular mechanisms regulating vulnerability to this process remain unclear. Here we report that microRNA-212 (miR-212) is upregulated in the dorsal striatum of rats with a history of extended access to cocaine. Stri...

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Main Authors: Hollander, Jonathan A., Im, Heh-In, Amelio, Antonio L., Kocerha, Jannet, Bali, Purva, Lu, Qun, Willoughby, David, Wahlestedt, Claes, Conkright, Michael D., Kenny, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916751/
https://ncbi.nlm.nih.gov/pubmed/20613834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09202
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