Mitogenic and drug-resistance mediating effects of PKCα require RLIP76

PKCα-activation is a key signaling event governing cell growth, stress-resistance, and drug-resistance. Our recent studies demonstrated that DOX-resistance mediating effects of PKCα require the presence of RLIP76, and their concerted action is sufficient to explain intrinsic DOX-resistance of NSCLC...

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Hlavní autoři: Singhal, Sharad S., Yadav, Sushma, Singhal, Jyotsana, Awasthi, Yogesh C., Awasthi, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916682/
https://ncbi.nlm.nih.gov/pubmed/16890208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.07.118
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