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Mitogenic and drug-resistance mediating effects of PKCα require RLIP76
PKCα-activation is a key signaling event governing cell growth, stress-resistance, and drug-resistance. Our recent studies demonstrated that DOX-resistance mediating effects of PKCα require the presence of RLIP76, and their concerted action is sufficient to explain intrinsic DOX-resistance of NSCLC...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916682/ https://ncbi.nlm.nih.gov/pubmed/16890208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.07.118 |
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