Evaluation of Colorimetric Methods Using Nicotinamide for Rapid Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis

The direct detection of pyrazinamide resistance in Mycobacterium tuberculosis is sufficiently difficult that many laboratories do not attempt it. Most pyrazinamide resistance is caused by mutations that inactivate the pyrazinamidase enzyme needed to convert the prodrug pyrazinamide to its active for...

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Bibliografski detalji
Glavni autori: Mirabal, Niuris C., Yzquierdo, Sergio L., Lemus, Dihadenys, Madruga, Mariela, Milián, Yoslaine, Echemendía, Miguel, Takiff, Howard, Martin, Anandi, Van der Stuyf, Patrick, Palomino, Juan Carlos, Montoro, Ernesto
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Mycobacteriology and Aerobic Actinomycetes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916567/
https://ncbi.nlm.nih.gov/pubmed/20554826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00311-10
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