Evaluation of Colorimetric Methods Using Nicotinamide for Rapid Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis

The direct detection of pyrazinamide resistance in Mycobacterium tuberculosis is sufficiently difficult that many laboratories do not attempt it. Most pyrazinamide resistance is caused by mutations that inactivate the pyrazinamidase enzyme needed to convert the prodrug pyrazinamide to its active for...

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Detalhes bibliográficos
Main Authors: Mirabal, Niuris C., Yzquierdo, Sergio L., Lemus, Dihadenys, Madruga, Mariela, Milián, Yoslaine, Echemendía, Miguel, Takiff, Howard, Martin, Anandi, Van der Stuyf, Patrick, Palomino, Juan Carlos, Montoro, Ernesto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916567/
https://ncbi.nlm.nih.gov/pubmed/20554826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00311-10
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