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Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection

Chronic hepatitis B virus (HBV) infections are associated with persistent immune killing of infected hepatocytes. Hepatocytes constitute a largely self-renewing population. Thus, immune killing may exert selective pressure on the population, leading it to evolve in order to survive. A gradual course...

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Detalhes bibliográficos
Main Authors: Mason, William S., Liu, Chen, Aldrich, Carol E., Litwin, Samuel, Yeh, Matthew M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916518/
https://ncbi.nlm.nih.gov/pubmed/20519397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00833-10
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