Detection of Clonally Expanded Hepatocytes in Chimpanzees with Chronic Hepatitis B Virus Infection

During a hepadnavirus infection, viral DNA integrates at a low rate into random sites in the host DNA, producing unique virus-cell junctions detectable by inverse nested PCR (invPCR). These junctions serve as genetic markers of individual hepatocytes, providing a means to detect their subsequent pro...

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Détails bibliographiques
Auteurs principaux: Mason, William S., Low, Huey-Chi, Xu, Chunxiao, Aldrich, Carol E., Scougall, Catherine A., Grosse, Arend, Clouston, Andrew, Chavez, Deborah, Litwin, Samuel, Peri, Suraj, Jilbert, Allison R., Lanford, Robert E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Transformation and Oncogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738144/
https://ncbi.nlm.nih.gov/pubmed/19535448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00700-09
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