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Transcriptional Activation of the Aldehyde Reductase YqhD by YqhC and Its Implication in Glyoxal Metabolism of Escherichia coli K-12

The reactive α-oxoaldehydes such as glyoxal (GO) and methylglyoxal (MG) are generated in vivo from sugars through oxidative stress. GO and MG are believed to be removed from cells by glutathione-dependent glyoxalases and other aldehyde reductases. We isolated a number of GO-resistant (GO(r)) mutants...

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Main Authors: Lee, Changhan, Kim, Insook, Lee, Junghoon, Lee, Kang-Lok, Min, Bumchan, Park, Chankyu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916428/
https://ncbi.nlm.nih.gov/pubmed/20543070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01127-09
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