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Drosophila von Hippel-Lindau Tumor Suppressor Gene Function in Epithelial Tubule Morphogenesis

Mutations in the human von Hippel-Lindau (VHL) gene are the cause of VHL disease that displays multiple benign and malignant tumors. The VHL gene has been shown to regulate angiogenic potential and glycolic metabolism via its E3 ubiquitin ligase function against the alpha subunit of hypoxia-inducibl...

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Hlavní autoři: Hsouna, Anita, Nallamothu, Gouthami, Kose, Nurgun, Guinea, Maria, Dammai, Vincent, Hsu, Tien
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916397/
https://ncbi.nlm.nih.gov/pubmed/20516215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01578-09
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