Pharmacokinetics and Pharmacodynamics of Amphotericin B Deoxycholate, Liposomal Amphotericin B, and Amphotericin B Lipid Complex in an In Vitro Model of Invasive Pulmonary Aspergillosis

The pharmacodynamic and pharmacokinetic (PK-PD) properties of amphotericin B (AmB) formulations against invasive pulmonary aspergillosis (IPA) are not well understood. We used an in vitro model of IPA to further elucidate the PK-PD of amphotericin B deoxycholate (DAmB), liposomal amphotericin B (LAm...

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Detalhes bibliográficos
Main Authors: Lestner, Jodi M., Howard, Susan J., Goodwin, Joanne, Gregson, Lea, Majithiya, Jayesh, Walsh, Thomas J., Jensen, Gerard M., Hope, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916353/
https://ncbi.nlm.nih.gov/pubmed/20439615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01586-09
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