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Mass Balance and Pharmacokinetics of [(14)C]Telavancin following Intravenous Administration to Healthy Male Volunteers
The mass balance and pharmacokinetics of telavancin, a semisynthetic lipoglycopeptide antimicrobial agent, were characterized in an open-label, phase 1 study of six healthy male subjects. After a single 1-h intravenous infusion of 10 mg/kg [(14)C]telavancin (0.68 μCi/kg), blood, urine, and feces wer...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916323/ https://ncbi.nlm.nih.gov/pubmed/20516282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01750-09 |
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