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Mass Balance and Pharmacokinetics of [(14)C]Telavancin following Intravenous Administration to Healthy Male Volunteers

The mass balance and pharmacokinetics of telavancin, a semisynthetic lipoglycopeptide antimicrobial agent, were characterized in an open-label, phase 1 study of six healthy male subjects. After a single 1-h intravenous infusion of 10 mg/kg [(14)C]telavancin (0.68 μCi/kg), blood, urine, and feces wer...

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Detalhes bibliográficos
Main Authors: Shaw, Jeng-Pyng, Cheong, Jonathan, Goldberg, Michael R., Kitt, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916323/
https://ncbi.nlm.nih.gov/pubmed/20516282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01750-09
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