Coxiella burnetii Phase I and II Variants Replicate with Similar Kinetics in Degradative Phagolysosome-Like Compartments of Human Macrophages

Coxiella burnetii infects mononuclear phagocytes, where it directs biogenesis of a vacuolar niche termed the parasitophorous vacuole (PV). Owing to its lumenal pH (∼5) and fusion with endolysosomal vesicles, the PV is considered phagolysosome-like. However, the degradative properties of the mature P...

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Detalhes bibliográficos
Main Authors: Howe, Dale, Shannon, Jeffrey G., Winfree, Seth, Dorward, David W., Heinzen, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916283/
https://ncbi.nlm.nih.gov/pubmed/20515926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00406-10
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