Coxiella burnetii Effector Proteins That Localize to the Parasitophorous Vacuole Membrane Promote Intracellular Replication

The intracellular bacterial pathogen Coxiella burnetii directs biogenesis of a parasitophorous vacuole (PV) that acquires host endolysosomal components. Formation of a PV that supports C. burnetii replication requires a Dot/Icm type 4B secretion system (T4BSS) that delivers bacterial effector protei...

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Udgivet i:Infect Immun
Main Authors: Larson, Charles L., Beare, Paul A., Voth, Daniel E., Howe, Dale, Cockrell, Diane C., Bastidas, Robert J., Valdivia, Raphael H., Heinzen, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294226/
https://ncbi.nlm.nih.gov/pubmed/25422265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02763-14
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