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Secreted Aspergillus fumigatus Protease Alp1 Degrades Human Complement Proteins C3, C4, and C5

The opportunistic human pathogenic fungus Aspergillus fumigatus is a major cause of fungal infections in immunocompromised patients. Innate immunity plays an important role in the defense against infections. The complement system represents an essential part of the innate immune system. This cascade...

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Hlavní autoři: Behnsen, Judith, Lessing, Franziska, Schindler, Susann, Wartenberg, Dirk, Jacobsen, Ilse D., Thoen, Marcel, Zipfel, Peter F., Brakhage, Axel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916278/
https://ncbi.nlm.nih.gov/pubmed/20498262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01353-09
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