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Secreted Aspergillus fumigatus Protease Alp1 Degrades Human Complement Proteins C3, C4, and C5

The opportunistic human pathogenic fungus Aspergillus fumigatus is a major cause of fungal infections in immunocompromised patients. Innate immunity plays an important role in the defense against infections. The complement system represents an essential part of the innate immune system. This cascade...

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Detalhes bibliográficos
Main Authors: Behnsen, Judith, Lessing, Franziska, Schindler, Susann, Wartenberg, Dirk, Jacobsen, Ilse D., Thoen, Marcel, Zipfel, Peter F., Brakhage, Axel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916278/
https://ncbi.nlm.nih.gov/pubmed/20498262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01353-09
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