The Staphylococcus aureus Epidermal Cell Differentiation Inhibitor Toxin Promotes Formation of Infection Foci in a Mouse Model of Bacteremia

Inactivation of the host GTPase RhoA by staphylococcal epidermal cell differentiation inhibitor (EDIN) exotoxins triggers the formation of large transcellular tunnels, named macroapertures, in endothelial cells. We used bioluminescent strains of Staphylococcus aureus to monitor the formation of infe...

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Main Authors: Munro, Patrick, Benchetrit, Maxime, Nahori, Marie-Anne, Stefani, Caroline, Clément, René, Michiels, Jean-François, Landraud, Luce, Dussurget, Olivier, Lemichez, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916266/
https://ncbi.nlm.nih.gov/pubmed/20479081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00319-10
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