The Staphylococcus aureus Epidermal Cell Differentiation Inhibitor Toxin Promotes Formation of Infection Foci in a Mouse Model of Bacteremia

Inactivation of the host GTPase RhoA by staphylococcal epidermal cell differentiation inhibitor (EDIN) exotoxins triggers the formation of large transcellular tunnels, named macroapertures, in endothelial cells. We used bioluminescent strains of Staphylococcus aureus to monitor the formation of infe...

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Bibliografiske detaljer
Main Authors: Munro, Patrick, Benchetrit, Maxime, Nahori, Marie-Anne, Stefani, Caroline, Clément, René, Michiels, Jean-François, Landraud, Luce, Dussurget, Olivier, Lemichez, Emmanuel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916266/
https://ncbi.nlm.nih.gov/pubmed/20479081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00319-10
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