Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid

The nonhuman sialic acid N-glycolylneuraminic acid (Neu5Gc) is metabolically incorporated into human tissues from certain mammalian-derived foods, and this occurs in the face of an anti-Neu5Gc “xeno-autoantibody” response. Given evidence that this process contributes to chronic inflammation in some...

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Detalhes bibliográficos
Main Authors: Taylor, Rachel E., Gregg, Christopher J., Padler-Karavani, Vered, Ghaderi, Darius, Yu, Hai, Huang, Shengshu, Sorensen, Ricardo U., Chen, Xi, Inostroza, Jaime, Nizet, Victor, Varki, Ajit
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916132/
https://ncbi.nlm.nih.gov/pubmed/20624889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100575
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