Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid

The nonhuman sialic acid N-glycolylneuraminic acid (Neu5Gc) is metabolically incorporated into human tissues from certain mammalian-derived foods, and this occurs in the face of an anti-Neu5Gc “xeno-autoantibody” response. Given evidence that this process contributes to chronic inflammation in some...

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Hlavní autoři: Taylor, Rachel E., Gregg, Christopher J., Padler-Karavani, Vered, Ghaderi, Darius, Yu, Hai, Huang, Shengshu, Sorensen, Ricardo U., Chen, Xi, Inostroza, Jaime, Nizet, Victor, Varki, Ajit
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916132/
https://ncbi.nlm.nih.gov/pubmed/20624889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100575
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