A Transient Kinetic Approach to Investigate Nucleoside Inhibitors of Mitochondrial DNA polymerase γ

Lignende værker

• A mechanistic view of human mitochondrial DNA polymerase γ: providing insight into drug toxicity and mitochondrial disease
  af: Bailey, Christopher M., et al.
  Udgivet: (2010)
• Mechanism of Interaction of Human Mitochondrial DNA Polymerase γ with the Novel Nucleoside Reverse Transcriptase Inhibitor 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine Indicates a Low Potential for Host Toxicity
  af: Sohl, Christal D., et al.
  Udgivet: (2012)
• Kinetic Investigation of the Inhibitory Effect of Gemcitabine on DNA Polymerization Catalyzed by Human Mitochondrial DNA Polymerase
  af: Fowler, Jason D., et al.
  Udgivet: (2008)
• An Analysis of Enzyme Kinetics Data for Mitochondrial DNA Strand Termination by Nucleoside Reverse Transcription Inhibitors
  af: Wendelsdorf, Katherine V., et al.
  Udgivet: (2009)
• R964C Mutation of DNA Polymerase γ Imparts Increased Stavudine Toxicity by Decreasing Nucleoside Analog Discrimination and Impairing Polymerase Activity
  af: Bailey, Christopher M., et al.
  Udgivet: (2009)