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Identification of Carcinogen DNA Adducts in Human Saliva by Linear Quadrupole Ion Trap/Multistage Tandem Mass Spectrometry

DNA adducts of carcinogens derived from tobacco smoke and cooked meat were identified, by liquid chromatography-electrospray ionization/multi-stage tandem mass spectrometry (LC-ESI/MS/MS(n)), in saliva samples from 37 human volunteers on unrestricted diets. The N-(deoxyguanosin-8-yl) (dG-C8) adducts...

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Detalhes bibliográficos
Main Authors: Bessette, Erin E., Spivack, Simon D., Goodenough, Angela K., Wang, Tao, Pinto, Shailesh, Kadlubar, Fred F., Turesky, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916027/
https://ncbi.nlm.nih.gov/pubmed/20443584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100098f
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