An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo

BACKGROUND: The physiological function of eukaryotic DNA occurs in the context of nucleosomal arrays that can expose or obscure defined segments of the genome. Certain DNA sequences are capable of strongly positioning a nucleosome in vitro, suggesting the possibility that favorable intrinsic signals...

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Bibliographic Details
Main Authors: Gracey, Lia E, Chen, Zhi-Ying, Maniar, Jay M, Valouev, Anton, Sidow, Arend, Kay, Mark A, Fire, Andrew Z
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915997/
https://ncbi.nlm.nih.gov/pubmed/20594331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-3-13
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