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Alzheimer's Disease and Down Syndrome Rodent Models Exhibit Audiogenic Seizures

Amyloid β-protein precursor (AβPP) is overexpressed in Alzheimer's disease (AD), Down syndrome (DS), autism and fragile × syndrome (F×S). Seizures are a common phenotype in all of these neurological disorders; yet, the underlying molecular mechanism(s) of seizure induction and propagation remai...

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Hlavní autoři: Westmark, Cara J., Westmark, Pamela R., Malter, James S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915889/
https://ncbi.nlm.nih.gov/pubmed/20413855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100087
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