Seizure Susceptibility and Mortality in Mice that Over-Express Amyloid Precursor Protein

Alzheimer's disease and Fragile X syndrome both display synaptic phenotypes, and based on recent studies, likely share dendritic over expression of amyloid precursor protein (APP) and β-amyloid (Aβ). In order to create a mouse model to specifically study the effects of APP and Aβ at synapses, w...

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Bibliografiske detaljer
Main Authors: Westmark, Cara J, Westmark, Pamela R, Beard, Ashley M, Hildebrandt, Sharon M, Malter, James S
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2008
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480559/
https://ncbi.nlm.nih.gov/pubmed/18784809
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