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Seizure Susceptibility and Mortality in Mice that Over-Express Amyloid Precursor Protein
Alzheimer's disease and Fragile X syndrome both display synaptic phenotypes, and based on recent studies, likely share dendritic over expression of amyloid precursor protein (APP) and β-amyloid (Aβ). In order to create a mouse model to specifically study the effects of APP and Aβ at synapses, w...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
e-Century Publishing Corporation
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2480559/ https://ncbi.nlm.nih.gov/pubmed/18784809 |
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