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True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair

Nucleotide excision repair (NER) is a major DNA repair pathway in eukaryotic cells. NER removes structurally diverse lesions such as pyrimidine dimers, arising upon UV irradiation or bulky chemical adducts, arising upon exposure to carcinogens and some chemotherapeutic drugs. NER defects lead to thr...

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Detalhes bibliográficos
Main Authors: Le May, Nicolas, Egly, Jean-Marc, Coin, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915888/
https://ncbi.nlm.nih.gov/pubmed/20725631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/616342
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