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True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair
Nucleotide excision repair (NER) is a major DNA repair pathway in eukaryotic cells. NER removes structurally diverse lesions such as pyrimidine dimers, arising upon UV irradiation or bulky chemical adducts, arising upon exposure to carcinogens and some chemotherapeutic drugs. NER defects lead to thr...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SAGE-Hindawi Access to Research
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915888/ https://ncbi.nlm.nih.gov/pubmed/20725631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/616342 |
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