Vascular Endothelial Growth Factor Receptor-2 Activates ADP-ribosylation Factor 1 to Promote Endothelial Nitric-oxide Synthase Activation and Nitric Oxide Release from Endothelial Cells

Vascular endothelial growth factor (VEGF) induces angiogenesis and regulates endothelial function via production and release of nitric oxide (NO), an important signaling molecule. The molecular basis leading to NO production involves phosphatidylinositiol-3 kinase (PI3K), Akt, and endothelial nitric...

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Detalhes bibliográficos
Main Authors: Daher, Zeinab, Boulay, Pierre-Luc, Desjardins, Fanny, Gratton, Jean-Philippe, Claing, Audrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915695/
https://ncbi.nlm.nih.gov/pubmed/20529868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115311
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