The Sodium Bicarbonate Cotransporter (NBCe1) Is Essential for Normal Development of Mouse Dentition

Proximal renal tubular acidosis (pRTA) is a syndrome caused by abnormal proximal tubule reabsorption of bicarbonate resulting in metabolic acidosis. Patients with mutations to the SLC4A4 gene (coding for the sodium bicarbonate cotransporter NBCe1), have pRTA, growth delay, ocular defects, and enamel...

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Autori principali: Lacruz, Rodrigo S., Nanci, Antonio, White, Shane N., Wen, Xin, Wang, HongJun, Zalzal, Sylvia F., Luong, Vivian Q., Schuetter, Verna L., Conti, Peter S., Kurtz, Ira, Paine, Michael L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915679/
https://ncbi.nlm.nih.gov/pubmed/20529845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115188
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