Nanoparticulate Radiolabelled Quinolines Detect Amyloid Plaques in Mouse Models of Alzheimer's Disease

Detecting aggregated amyloid peptides (Aβ plaques) presents targets for developing biomarkers of Alzheimer's disease (AD). Polymeric n-butyl-2-cyanoacrylate (PBCA) nanoparticles (NPs) were encapsulated with radiolabelled amyloid affinity (125)I-clioquinol (CQ, 5-chloro-7-iodo-8-hydroxyquinoline...

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Detalhes bibliográficos
Main Authors: Roney, Celeste A., Arora, Veera, Kulkarni, Padmakar V., Antich, Peter P., Bonte, Frederick J.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915660/
https://ncbi.nlm.nih.gov/pubmed/20721294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2009/481031
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