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Effect of Microwave Radiation on Enzymatic and Chemical Peptide Bond Synthesis on Solid Phase

Peptide bond synthesis was performed on PEGA beads under microwave radiations. Classical chemical coupling as well as thermolysin catalyzed synthesis was studied, and the effect of microwave radiations on reaction kinetics, beads' integrity, and enzyme activity was assessed. Results demonstrate...

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Détails bibliographiques
Auteurs principaux: Basso, Alessandra, Sinigoi, Loris, Gardossi, Lucia, Flitsch, Sabine
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915653/
https://ncbi.nlm.nih.gov/pubmed/20721296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/362482
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