Genetic variations of the PI3K–AKT–mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients

The phosphoinositide-3 kinase (PI3K)–AKT– mammalian target of rapamycin (mTOR) pathway is an important cellular pathway controlling cell growth, tumorigenesis, cell invasion and drug response. We hypothesized that genetic variations in the PI3K–AKT–mTOR pathway may affect the survival in muscle inva...

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Autori principali: Chen, Meng, Gu, Jian, Delclos, George L., Killary, Ann M., Fan, Zhen, Hildebrandt, Michelle A. T., Chamberlain, Robert M., Grossman, H. Barton, Dinney, Colin P., Wu, Xifeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Molecular Epidemiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915631/
https://ncbi.nlm.nih.gov/pubmed/20530239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq110
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