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Intracellular Ca(2+) and TRPM5-mediated membrane depolarization produce ATP secretion from taste receptor cells

ATP is a transmitter secreted from taste bud receptor (Type II) cells through ATP-permeable gap junction hemichannels most probably composed of pannexin 1. The elevation of intracellular Ca(2+) and membrane depolarization are both believed to be involved in transmitter secretion from receptor cells,...

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Main Authors: Huang, Yijen A, Roper, Stephen D
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915511/
https://ncbi.nlm.nih.gov/pubmed/20498227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.191106
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