Efficient Genome-Wide Association Testing of Gene-Environment Interaction in Case-Parent Trios

Complex trait variation is likely to be explained by the combined effects of genes, environmental factors, and gene × environment (G × E) interaction. The authors introduce a novel 2-step method for detecting a G × E interaction in a genome-wide association study (GWAS) of case-parent trios. The met...

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Bibliographic Details
Main Authors: Gauderman, W. James, Thomas, Duncan C., Murcray, Cassandra E., Conti, David, Li, Dalin, Lewinger, Juan Pablo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Practice of Epidemiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915477/
https://ncbi.nlm.nih.gov/pubmed/20543031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwq097
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