Placebo-Controlled Randomized Trial of Adjuvant Imatinib Mesylate Following the Resection of Localized, Primary Gastrointestinal Stromal Tumor (GIST)

BACKGROUND: Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the intestinal tract. The standard treatment of localized, primary GIST has been surgical resection alone. Most GISTs have a mutation in the KIT proto-oncogene, or less commonly in platelet-derived growth factor receptor...

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Hauptverfasser: DeMatteo, Ronald P., Ballman, Karla V., Antonescu, Cristina R., Maki, Robert G., Pisters, Peter W.T., Demetri, George D., Blackstein, Martin E., Blanke, Charles D., von Mehren, Margaret, Brennan, Murray F., Patel, Shreyaskumar, McCarter, Martin D., Polikoff, Jonathan A., Tan, Benjamin R., Owzar, Kouros
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915459/
https://ncbi.nlm.nih.gov/pubmed/19303137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(09)60500-6
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