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Chaperone-mediated autophagy: Molecular mechanisms and physiological relevance

Chaperone-mediated autophagy (CMA) is a selective lysosomal pathway for the degradation of cytosolic proteins. We review in this work some of the recent findings on this pathway regarding the molecular mechanisms that contribute to substrate targeting, binding and translocation across the lysosomal...

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Autors principals: Orenstein, Samantha J., Cuervo, Ana Maria
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914824/
https://ncbi.nlm.nih.gov/pubmed/20176123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2010.02.005
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