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MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

BACKGROUND: MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes via regulation of cell proliferation and/or apoptosis. MiR-221 and miR-222 were discovered to induce cell growth and cell cycle progression via direct targeting of p27 and p57 in various human malignancies. How...

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Autors principals: Chun-zhi, Zhang, Lei, Han, An-ling, Zhang, Yan-chao, Fu, Xiao, Yue, Guang-xiu, Wang, Zhi-fan, Jia, Pei-yu, Pu, Qing-yu, Zhang, Chun-sheng, Kang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914702/
https://ncbi.nlm.nih.gov/pubmed/20618998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-367
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