MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

BACKGROUND: Substantial data indicate that the oncogene microRNA 21 (miR-21) is significantly elevated in glioblastoma multiforme (GBM) and regulates multiple genes associated with cancer cell proliferation, apoptosis, and invasiveness. Thus, miR-21 can theoretically become a target to enhance the c...

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Detalhes bibliográficos
Main Authors: Ren, Yu, Zhou, Xuan, Mei, Mei, Yuan, Xu-Bo, Han, Lei, Wang, Guang-Xiu, Jia, Zhi-Fan, Xu, Peng, Pu, Pei-Yu, Kang, Chun-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824710/
https://ncbi.nlm.nih.gov/pubmed/20113523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-27
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