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A Versatile Approach to Transform Low-Affinity Peptides into Protein Probes with Co-Translationally Expressed Chemical Cross-Linker

The potential usefulness of artificially selected peptides as probes to detect specific proteins has been proposed because of the ease and low cost of syntheses, manipulation and genetic expression. However, the affinities of these peptides to their target proteins are generally too low to be practi...

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Autors principals: Umeda, Aiko, Thibodeaux, Gabrielle Nina, Moncivais, Kathryn, Jiang, Faqin, Zhang, Zhiwen Jonathan
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914685/
https://ncbi.nlm.nih.gov/pubmed/20510935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.05.026
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