Scheduling of Radiation with Angiogenesis Inhibitors Anginex and Avastin Improves Therapeutic Outcome via Vessel Normalization

PURPOSE: To test whether a direct antiangiogenic peptide (anginex) and a vascular endothelial growth factor antibody (bevacizumab, Avastin) can transiently normalize vasculature within tumors to improve oxygen delivery, alleviate hypoxia, and increase the effect of radiation therapy. EXPERIMENTAL DE...

Full description

Saved in:
Bibliographic Details
Main Authors: Dings, Ruud P.M., Loren, Melissa, Heun, Hanke, McNiel, Elizabeth, Griffioen, Arjan W., Mayo, Kevin H., Griffin, Robert J.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914684/
https://ncbi.nlm.nih.gov/pubmed/17545548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-2441
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items