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Altered levels and distribution of APP and its processing enzymes in Niemann-Pick Type C1-deficient mouse brains

Niemann-Pick type C (NPC) disease is an autosomal recessive neurodegenerative disorder characterized by intracellular accumulation of cholesterol and glycosphingolipids in many tissues including the brain. The disease is caused by mutations of either NPC1 or NPC2 gene and is accompanied by a severe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kodam, A., Maulik, M., Peake, K., Amritraj, A., Vetrivel, K.S., Thinakaran, G., Vance, J.E., Kar, S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914615/
https://ncbi.nlm.nih.gov/pubmed/20607864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21001
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