Tumor-specific recombinant idiotype immunisation after chemotherapy as initial treatment for follicular non-Hodgkin lymphoma

Tumor-specific variable regions of the clonal immunoglobulin (idiotype, Id) expressed by B cell non-Hodgkin lymphoma (NHL) can be targeted by active immunotherapy. We conducted a phase I/II trial to determine the safety and immunogenicity of a patient-specific, recombinant, mammalian cell-derived Id...

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Hlavní autoři: Timmerman, John M., Vose, Julie M., Czerwinski, Debra K., Weng, Wen-Kai, Ingolia, Diane, Mayo, Martha, Denney, Dan W., Levy, Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914563/
https://ncbi.nlm.nih.gov/pubmed/19125383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428190802563355
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