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Acetylation Is Indispensable for p53 Activation
The activation of the tumor suppressor p53 facilitates the cellular response to genotoxic stress; however, the p53 response can only be executed if its interaction with its inhibitor Mdm2 is abolished. There have been conflicting reports on the question of whether p53 posttranslational modifications...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914560/ https://ncbi.nlm.nih.gov/pubmed/18485870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.03.025 |
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