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TLR4-Mediated Signaling Induces MMP9-Dependent Cleavage of B Cell Surface CD23

IgE production is inversely regulated by circulating and B cell surface levels of the low affinity IgE receptor, CD23. To begin to understand physiologic determinants of CD23 expression, we analyzed effects of BCR and TLR stimulation on CD23 levels. BCR and TLR 2, 3, 4, 6, and 9 agonists induced CD2...

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Autors principals: Jackson, Leila, Cady, Carol T., Cambier, John C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914506/
https://ncbi.nlm.nih.gov/pubmed/19635918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803660
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