Dual Effect of Neutrophils on pIgR/Secretory Component in Human Bronchial Epithelial Cells: Role of TGF-β

Neutrophils have a dual affect on epithelial pIgR/SC, the critical receptor for transcellular routing of mucosal IgA, but mechanisms of pIgR/SC upregulation remain elusive. Requirements of cytokine, redox, and signalling pathways for pIgR/SC production were assessed in human bronchial epithelial (Ca...

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Main Authors: Ratajczak, Céline, Guisset, Amélie, Detry, Bruno, Sibille, Yves, Pilette, Charles
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914448/
https://ncbi.nlm.nih.gov/pubmed/20706611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/428618
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