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LPS induces IL-10 production by human alveolar macrophages via MAPKinases- and Sp1-dependent mechanisms
BACKGROUND: IL-10 is a cytokine mainly produced by macrophages that plays key roles in tolerance to inhaled antigens and in lung homeostasis. Its regulation in alveolar macrophages (HAM), the resident lung phagocytes, remains however unknown. METHODS: The present study investigated the role of intra...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080632/ https://ncbi.nlm.nih.gov/pubmed/17916230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-8-71 |
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