Computational Method for Estimating DNA Copy Numbers in Normal Samples, Cancer Cell Lines, and Solid Tumors Using Array Comparative Genomic Hybridization

Genomic copy number variations are a typical feature of cancer. These variations may influence cancer outcomes as well as effectiveness of treatment. There are many computational methods developed to detect regions with deletions and amplifications without estimating actual copy numbers (CN) in thes...

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Detalhes bibliográficos
Main Authors: Abkevich, Victor, Iliev, Diana, Timms, Kirsten M., Tran, Thanh, Skolnick, Mark, Lanchbury, Jerry S., Gutin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914423/
https://ncbi.nlm.nih.gov/pubmed/20706610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/386870
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