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Computational Method for Estimating DNA Copy Numbers in Normal Samples, Cancer Cell Lines, and Solid Tumors Using Array Comparative Genomic Hybridization

Genomic copy number variations are a typical feature of cancer. These variations may influence cancer outcomes as well as effectiveness of treatment. There are many computational methods developed to detect regions with deletions and amplifications without estimating actual copy numbers (CN) in thes...

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書誌詳細
主要な著者: Abkevich, Victor, Iliev, Diana, Timms, Kirsten M., Tran, Thanh, Skolnick, Mark, Lanchbury, Jerry S., Gutin, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914423/
https://ncbi.nlm.nih.gov/pubmed/20706610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/386870
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