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Differences between Newborn and Adult Mice in Their Response to Immune Thrombocytopenia

BACKGROUND: Sick neonates frequently develop severe thrombocytopenia. Objective and Methods: In order to test the ability of fetal mice to increase their megakaryocyte size and ploidy in response to thrombocytopenia, we injected an antiplatelet antibody (MWReg30) into pregnant mice daily for 7 days,...

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Autori principali: Hu, Zhongbo, Slayton, William B., Rimsza, Lisa M., Bailey, Matthew, Sallmon, Hannes, Sola-Visner, Martha C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914362/
https://ncbi.nlm.nih.gov/pubmed/20134184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000280413
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