Differential effects of recombinant thrombopoietin and bone marrow stromal-conditioned media on neonatal versus adult megakaryocytes

Umbilical cord blood (CB) is a valuable source of stem cells for transplantation, but CB transplantations are frequently complicated by delayed platelet engraftment. The reasons underlying this are unclear. We hypothesized that CB- and peripheral-blood (PB)–derived megakaryocytes (MKs) respond diffe...

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Detalhes bibliográficos
Main Authors: Pastos, Karen M., Slayton, William B., Rimsza, Lisa M., Young, Linda, Sola-Visner, Martha C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895431/
https://ncbi.nlm.nih.gov/pubmed/16888093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-018036
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