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New Insights Concerning the Glucose-dependent Insulin Secretagogue Action of Glucagon-like Peptide-1 in Pancreatic β-Cells
The GLP-1 receptor is a Class B heptahelical G-protein-coupled receptor that stimulates cAMP production in pancreatic β-cells. GLP-1 utilizes this receptor to activate two distinct classes of cAMP-binding proteins: protein kinase A (PKA) and the Epac family of cAMP-regulated guanine nucleotide excha...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914250/ https://ncbi.nlm.nih.gov/pubmed/15655710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-2004-826165 |
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