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Viral-mediated Expression of Extracellular Signal-Regulated Kinase-2 in the Ventral Tegmental Area Modulates Behavioral Responses to Cocaine

Chronic exposure to cocaine increases the activity of extracellular signal-regulated kinase (ERK1/2) in the ventral tegmental area (VTA), a neural substrate for drugs of abuse. However, the functional significance of changes in ERK1/2 activity in this brain region is unknown. Using herpes simplex vi...

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Detalhes bibliográficos
Main Authors: Iñiguez, Sergio D, Warren, Brandon L, Neve, Rachael L, Russo, Scott J, Nestler, Eric J, Bolaños-Guzmán, Carlos A
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914184/
https://ncbi.nlm.nih.gov/pubmed/20561901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2010.05.040
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