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Insulin Receptor Substrate-2 in the Ventral Tegmental Area Regulates Behavioral Responses to Cocaine

Neurotrophic factor signaling modulate cellular and behavioral responses to drugs of abuse. Chronic exposure to abused drugs, among other biochemical adaptations, decreases the expression of Insulin Receptor Substrate-2 (IRS-2; a protein involved in neurotrophic signaling) in the ventral tegmental a...

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Autors principals: Iñiguez, Sergio D., Warren, Brandon L., Neve, Rachael L., Nestler, Eric J., Russo, Scott J., Bolaños-Guzmán, Carlos A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562620/
https://ncbi.nlm.nih.gov/pubmed/18823173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0012893
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